Hemolock Hemostatic Granules: The Science Behind and Our Cutting Edges
2023-04-04
About Hemolock™
Hemolock™ is a Carboxymethyl Chitosan hemostat designed to stop lethal bleeding fast. It has better performance than normal Chitosan hemostat.
Hemolock™ is a Sterile, Single-use, High-absorbent hemostatic granules intended to be used to temporary control of bleeding wounds, as below:
1. Arterial & Venous bleeding
2. Gunshot wounds
3. Blast Injuries
4. Puncture or stab wounds
5. Cuts, lacerations
Hemolock™ is an easy-to-use, highly effective, and safe wound treatment solution available in different delivery systems including pouch and syringe applicator.
It has been designed to assist caregivers in treating a variety of deep and difficult wounds.
Unlike traditional Chitosan hemostats that contain acidic additives, Hemolock™ has the same pH as the human body, ensuring that it does not cause any irritation or discomfort.
Furthermore, it does not generate heat, making it a safe option for both the casualty and caregiver.
Hemolock™ works independently of the body’s normal clotting processes and has been proven to be effective even in hypothermic conditions and in the presence of common anticoagulants such as Coumadin and Heparin.
Its clotting ability has been extensively tested and verified.
How Does Hemolock™ Work?
Hemolock™ granules have dual function of blood clotting:
1. Hemolock contains abundant hydrophilic carboxymethyl, combined with high surface-area flakes that rapidly absorb fluid from blood.
2. Moreover, when directly placed into a bleeding wound and compressed, the positively charged Hemolock cross-links with negatively charged red blood cells, causing it to swell, gel, and adhere together to form a robust pseudo-clot. This adhesive-like action effectively seals the wound and rapidly controls bleeding. Additionally, the Hemolock clot adheres well to moist tissue, preventing it from easily dislodging during the movement of the wounded person and causing secondary harm.
Hemolock™ is a highly specialized wound treatment solution that operates independently of the body’s normal clotting cascade. It is designed to clot only the blood it comes into direct contact with and cannot enter the bloodstream. Unlike other hemostats, Hemolock™ does not set off a blood clotting response that could cause clots to form at a distance from the product. This unique mechanism of action ensures that Hemolock™ only targets the affected area, reducing the risk of complications and adverse reactions. Its focused clotting ability makes it an effective and safe solution for managing deep and difficult wounds.
Carboxymethyl Chitosan
Hemolock™ is composed of Carboxymethyl chitosan, an innovative material that addresses the shortcomings of Chitosan while retaining its advantages. Carboxymethyl chitosan is created by adding negatively charged hydrophilic carboxyl groups to chitosan molecules. This modification results in a molecule with both a physiologically active amino group and a positive charge, as well as a negative charge. As a result, Carboxymethyl chitosan is soluble in water, making it an excellent material for use in the human body.
Due to the negative charges and carboxyl groups present in its molecular structure, Carboxymethyl chitosan is highly water-soluble and biocompatible. It is very similar to the extracellular matrix components found in the body environment, such as hyaluronic acid, collagen, and other glycosaminoglycans, all of which are negatively charged macromolecules containing carboxyl groups. This biocompatibility ensures that Carboxymethyl chitosan does not cause any inflammatory response when used in the human body. Overall, Hemolock™’s use of Carboxymethyl chitosan makes it a safe and effective option for managing deep and difficult wounds.
Carboxymethyl chitosan retains the original amino group (-NH3) and positive charge of chitosan, allowing it to maintain the physiological activity of chitosan. Additionally, Carboxymethyl chitosan possesses improved solubility and biocompatibility due to the incorporation of negatively charged hydrophilic carboxyl groups.
Our chitosan is derived from North Atlantic snow crab shells, ensuring that it is free from contamination and heavy metals. Chitosan has been extensively studied and proven to possess antimicrobial properties, making it an effective solution for managing wounds. Unlike other hemostats, chitosan is not procoagulant, ensuring that it does not trigger an unwanted clotting response.
Moreover, Carboxymethyl chitosan is highly biocompatible with human body cells, as it is broken down and absorbed through normal metabolic pathways. It has a long history of use in vascular closure and human cardiac surgery, demonstrating its effectiveness and safety.
Why use Hemolock™？
• Proven to control arterial bleeding within 30 seconds
• Rapid clotting
• Works in hypothermic conditions
• works on anticoagulated blood
• Strong wound adhesion
• Similar to human physiological pH, no stimulation
• No heat – no burning
• Sterile, waterproof packaging
• Easy to wash from wound with water or saline – no debridement necessary,
•Bio-material, easy degraded， the remaining will be safely absorbed because it is bio-compatible and bio-absorbable.
• Applied using basic first aid skills
• Reduces risk related to spread of blood-borne pathogens
• It is natural and highly purified – no allergic reactions in the history of its use.
• No reports of Hemolock™ having failed or underperformed In the history of its use
Bleeding can be a serious and life-threatening issue, especially in medical emergencies, trauma, and surgical procedures. It is essential to control bleeding quickly and effectively to prevent complications and save lives. Chitosan as its main ingredient, Hemolock Hemostatic Granules (HHC) is a reliable and efficient solution for bleeding.
The Science behind Hemolock Hemostatic Granules-The blood clot powder
Chitosan is a natural biopolymer that is derived from the shells of crustaceans such as shrimp and crabs. When chitosan comes into contact with blood, it forms a gel-like substance that rapidly clots the blood, forms the wound clot and stops bleeding. Chitosan works by binding to the blood cells and platelets to create a stable clot that seals the wound.
Cutting Edges of Hemolock Hemostatic Granules in wound care-Powder that stops bleeding
Quick and Effective: HHC stops bleeding within seconds, making it a reliable option in emergency situations.
Easy to Use: HHC is easy to apply, whether it’s in the field or in clinical settings.
Versatile: HHC can be used on a variety of wounds, including lacerations, punctures, and abrasions.
Safe: HHC is safe to use and has no known adverse effects.
Cost-effective: HHC is a cost-effective solution compared to traditional wound care methods.
